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| I have not been able to find any information about the safety of taking Bextra (valdecoxib) while nursing. Do you have any information about this? |
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Heather:
No data is available, but I have a research project just getting started with this drug. I'm pretty sure its milk levels will be extremely LOW.
Tom Hale, Ph.D.
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| Is there any more information on this medication now? My client was diagnosed with a new case of arthritis prior to her last pregnancy. She was given some "sample" meds, but due to the pregnancy did not start any therapy. Now 2 months after her delivery - her sixth_ she does need to start something. Her infant was a 36 week delivery with a brief NICU stay,and is gaining well now. Mom has a history that is suspicious to me of oversupply-hyperlactation. We talked a lot about that and she reports that this baby nurses one breast per feed and she feels things are going well. Her orthopedic doctor of course is concerned about all meds and breastfeeding. The meds he had suggested are: Vioxx, and Bextra, which she has samples, and celebrex. The only med she had doseages on was the bextra; 20 mg 1-2 x daily. From your text the celebrex appears to be the best choice, but I wanted to see if there was anything more definate on bextra, and if you had any other suggestions. |
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Martha:
I am just now publishing data on celecoxib(Celebrex). The amount of transfer to the infant is very low, only 0.3% of the maternal dose.
When we studied several women who took 20 mg valdecoxib(Bextra), I was unable to determine milk levels because they were too low to be detected by my instrument...hence they are even lower than celecoxib.
I do not think at this time , that any of these 'coxib' derivatives are going to be hazardous to use in breastfeeding mothers.
Tom Hale Ph.D. |
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